Breast cancer is a type of cancer that starts in the cells of the breast. It is one of the most common cancers in women worldwide, but it can also affect men. Breast cancer occurs when the cells in the breast grow uncontrollably, forming a tumor that can be detected through imaging or felt as a lump.
The main objective of Breast-Conserving Surgery (BCS) is to remove cancerous tumors with clear margins during the initial operation to avoid the need for additional surgery. If there are still cancerous cells at the edges of the removed tissue, there is a higher risk of the cancer coming back, leading to additional medical expenses and causing mental and physical stress.
Checking the margins of the surgical cavity immediately after tumor removal can help ensure that no cancerous cells are left behind, and the Cancer Diagnostic Probe product is specifically designed for this purpose. The Cancer Diagnostic Probe (CDP) is utilized in conjunction with frozen-section and permanent pathologies to identify high-risk pre-cancer/cancer cells in cavity side margins and cancerous cells in the lymph nodes of breast cancer surgery patients in real-time.
The Efficiency of Cancer Diagnostic Probe in Breast Cancer
Directly checking the margins of the cavity after tumor excision can help prevent any remaining tumor residues, satellite, or scattered cancer cells. Published reports have indicated that conventional intraoperative methods, such as frozen section and X-ray evaluation of dissected tumor margins, still miss diagnosing more than 20% of the involved margins.
It is also important to remove all the involved lymph nodes from the body to reduce the risk of local recurrences. The Cancer Diagnostic Probe (CDP) is a real-time diagnostic system that serves as a complementary surgeon-assisted tool. It is used in conjunction with frozen-section and permanent pathologies to detect high-risk pre-cancer/cancer cells in the cavity side margins and cancerous cells in the lymph nodes of patients undergoing breast cancer surgery.
In modern cancer therapy, these probes play a crucial role due to their precision and ability to provide detailed information about the presence and characteristics of cancer. This ultimately leads to improved diagnosis, treatment, and patient outcomes.
Cancer Diagnostic Probe Description
Checking the cavity-side margins during surgery for breast cancer patients is critical to ensure the definitive removal of suspicious and high-risk lesions with minimal damage to normal tissue. Remaining cancer cells in the breast causes re-surgeries and inevitable post-surgical treatments, which will have several side effects. Frozen pathology of tumor margins during surgery is a clinically accepted procedure to guide the surgeon to any need for re-excision. However, the time-consuming and expert dependent process of margin examination and false diagnostics, especially in neoadjuvant cases, are limitations of this procedure. CDP ( Cancer Diagnostic Probe ) system, has been introduced as a surgical assistant system in breast cancer surgery.
The new system reveals the cancerous cells in the internal margins (cavity-side margin) within a few millimeters in 40 seconds, using a needle sensor. This system has a clinical diagnostic classification matching with the pathological results of the tested tissues. The CDP response peaks are based on the classification of the pathological system (Ductal intraepithelial neoplasia (DIN), Lobular intraepithelial neoplasia (LIN), and Fibro epithelial lesion (FEL) (according to the latest reported revisions)).
The distinctive ability of CDP to detect cancer cells in the internal margins (after tumor dissection) has the sensitivity and selectivity of 97% and 94%, respectively.
Hospitech Cancer Diagnostic Probe
Hospitech Cancer Care Innovations Company is leading the way in revolutionizing cancer diagnosis with its innovative range of devices. These include the Cancer Diagnostic Probe (CDP), Impedimetric Tumor Detection System (ITDS), Electrical Endoscopy Mass Detection (EMD), and ElectroChemoTherapy (ECT) & Gamma Probe. These cutting-edge technologies are designed to improve cancer detection and treatment efficacy. Supported by research, articles, and patents, these tools provide accurate results for early diagnosis and better patient outcomes. The company takes pride in its dedicated team and unwavering commitment to making a significant impact in the healthcare industry’s fight against cancer.
Upgrade your medical center by utilizing Hospital Tech’s breast cancer diagnostic product and benefit from an innovative and safe approach to breast tumor surgery and treatment.
- Applying an LN headprobe on an auxiliary lymph node to detect LN involvement
- Hematic view of a lymph node free of cancerous cells
- The metabolism of cancer cells in the primary tumor site based on taking glucose from blood vessels (hypoxia glycolysis)
- Schematic view of cancer cells spreading from the primary tumor site and invasion to a lymph node environment through lymphatic vessels
- With the metabolic shift of cancer cells to Fatty Acid Oxidation (FAO)
- Dimensions of an LN headprobe
Statistical Diagnostic Results of CDP ( Cancer Diagnostic Probe ) in the margin and Lymph nodes
* Percentage reduction of the involved margins remaining in the patient’s body with the help of CDP despite performing Frozen-section and Permanent Pathology on tumor side margins (%)
Mohammad Abdolahad
Mohammad Abdolahad was born in Tehran, Iran, in 1982. He received his Ph.D. in Nanoelectronic Engineering from the University of Tehran in 2013. Immediately, he started teaching as an academic staff member in the College of Engineering, the School of Electrical and Computer Engineering. In the last few years, he has published more than 70 articles. He has 45 US patents in the field of cancer diagnosis and treatment devices ( Cancer Diagnostic Probe ). He has won many honors, including the Mustafa Award (2019), Selected Researcher of the Country (2019), Selected Young Researcher in 2017, etc.
