Checking the cavity-side margins during surgery for breast cancer patients is critical to ensure the definitive removal of suspicious and high-risk lesions with minimal damage to normal tissue. Remaining cancer cells in the breast causes re-surgeries and inevitable post-surgical treatments, which will have several side effects. Frozen pathology of tumor margins during surgery is a clinically accepted procedure to guide the surgeon to any need for re-excision. However, the time-consuming and expert dependent process of margin examination and false diagnostics, especially in neoadjuvant cases, are limitations of this procedure. The CDP (Cancer Diagnosis Probe) system, developed for the first time globally, is based on the real-time electrochemical measurement of the hypoxia glycolysis metabolism in pre-cancerous and cancerous lesions in cavity side margins during the surgery.

References:

Miripour ZS, Abbasvandi F, Aghaee P, et al. Electrochemical tracing of Hypoxia glycolysis by carbon nanotube sensors, a new hallmark for intra‐operative detection of suspicious margins to breast neoplasia. Bioeng Transl Med. e10236. – PMCPubMed

A Revolution In Breast Cancer Diagnosis

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